INTERNATIONAL JOURNAL OF APPLIED PHARMACEUTICAL SCIENCES AND RESEARCH <div class="row"> <div class="col-md-4 text-center"><img src="/public/site/images/sjadmin/IJAPSR.jpg"></div> <div class="col-md-8"> <p>IJAPSR is a peer-reviewed, open-access journal published quarterly by Sierra Journals Publisher. The journal publishes original work like a research article, review article, case study, short communication, and letter to the editor. The journal covers various subjects related to pharmaceutical and applied sciences.</p> <p>The journal aims to promote basic research into clinical investigation and convert clinical evidence into practical knowledge. We encourage papers referring to global medical studies of human health.</p> <p>Sierra Journals Publisher is a member of Crossref, thus the journal provides digital object identifier, LOCKSS preservation for its content followed by indexing in good indexing agencies</p> <p>&nbsp;</p> </div> </div> <div class="row"> <div id="additionalHomeContent" class="col-md-12"> <p>ISSN NO: 2455-8095&nbsp;&nbsp;&nbsp;&nbsp; Doi prefix: 10.21477&nbsp;&nbsp; &nbsp;</p> &nbsp;&nbsp; <div id="myCarousel" class="carousel slide"><!-- Carousel items --> <div class="carousel-inner"> <div class="item active"> <div class="row-fluid"> <div class="col-md-3 col-xs-6"><a href="" target="_blank" rel="noopener"><img src="/public/site/images/sjadmin/logo15.png"></a></div> <div class="col-md-3 col-xs-6"><a href="" target="_blank" rel="noopener"><img src="/public/site/images/sjadmin/logo21.png"></a></div> <div class="col-md-3 col-xs-6"><a href=";q=international+journal+of+applied+pharmaceutical+sciences+and+research&amp;btnG=" target="_blank" rel="noopener"><img src="/public/site/images/sjadmin/logo31.png"></a></div> <div class="col-md-3 col-xs-6"><img src="/public/site/images/sjadmin/logo53.png"></div> </div> <!--/row-fluid--></div> <!--/item--> <div class="item"> <div class="row-fluid"> <div class="col-md-3 col-xs-6"><a href="" target="_blank" rel="noopener"><img src="/public/site/images/sjadmin/logo71.png"></a></div> <div class="col-md-3 col-xs-6"><img src="/public/site/images/sjadmin/logo83.png"></div> <div class="col-md-3 col-xs-6"><a href="" target="_blank" rel="noopener"><img src="/public/site/images/sjadmin/logo91.png"></a></div> <div class="col-md-3 col-xs-6"><img src="/public/site/images/sjadmin/logo111.png"></div> </div> <!--/row-fluid--></div> <!--/item--> <div class="item"> <div class="row-fluid"> <div class="col-md-3 col-xs-6"><a href=";searchTerm=International%20Journal%20of%20Applied%20Pharmaceutical%20Sciences%20and%20Research&amp;start=1&amp;count=10&amp;libTypeNum=0&amp;sortBy=rel" target="_blank" rel="noopener"><img src="/public/site/images/sjadmin/logo121.png"></a></div> <div class="col-md-3 col-xs-6"><a href="" target="_blank" rel="noopener"><img src="/public/site/images/sjadmin/logo131.png"></a></div> <div class="col-md-3 col-xs-6"><a href="" target="_blank" rel="noopener"><img src="/public/site/images/sjadmin/logo41.png"></a></div> </div> <!--/row-fluid--></div> <!--/item--></div> <!--/carousel-inner--> <a class="left carousel-control" href="#myCarousel" data-slide="prev">‹</a> <a class="right carousel-control" href="#myCarousel" data-slide="next">›</a></div> <!--/myCarousel--></div> </div> Sierra Journals Publisher en-US INTERNATIONAL JOURNAL OF APPLIED PHARMACEUTICAL SCIENCES AND RESEARCH 2455-8095 Antifungal Finishing of Fabrics with Natural Dyes from Aerial Biomass of Perilla frutescens (L.) Britton <p>Increased environmental consciousness coupled with detrimental impacts of synthetic dyes and consumers’ concern over hygiene, cleanliness and protection, the demand for functional textiles has increased in recent years. Antimicrobial finishing imparts protective properties to textiles besides attractive shades. The study was aimed to determine the antifungal activity of colourants from aerial biomass of Perilla frutescens and dyed fabrics against pathogenic fungi infesting textiles materials. Antifungal activity of natural dye extracted from aerial biomass of Perilla frutescens against the selected pathogenic fungi viz., Aspergillus niger, Aspergillus flavus, Fusarium moniliforme, Fusarium solani, and Penicillium decumbens was evaluated by agar-well diffusion method. The MIC of the natural dye against each of the test fungi was determined by broth dilution method. Dyed silk, wool and cotton fabrics were also evaluated for antifungal activity by standard method. The natural dye showed antifungal activity against all the five test fungi in a concentration dependent manner. The treatment dose of 1000μg/ml recorded the highest growth reduction in all the test fungi, nearly at par with the positive control. The MICs of natural dye against the test fungi ranged from 32.39 to 36.50μg/ml. All kinds of dyed fabrics also showed remarkable antifungal efficacy against the test fungi. Dyed wool fabric exhibited the maximum growth reduction followed by silk and cotton. The result of the study demonstrated the remarkable antifungal activity of natural dye from Perilla frutescens aerial biomass and dyed fabrics. Therefore, Perilla frutescens can be considered as a potential source of natural dye with functional properties and can be used in protective finishing of different kinds of textile fabrics.</p> Anita Pal Rakesh Kumar Yogesh Chandra Tripathi ##submission.copyrightStatement## 2021-01-01 2021-01-01 6 01 8 14 10.21477/ijapsr.6.1.2 Treatment with Corticosteroids may Link to Higher Risk of COVID-19 Disease? Corticosteroids are one of the important natural hormones released in the body that play a vital role in metabolism due to their intense anti-inflammatory, immunomodulatory and immune suppressive activity. These are most prescribed medications available in various dosage forms like topical formulations, inhalers and injectables. The current outbreak of corona virus disease COVID-19 became a global threat and primary concern worldwide. In respiratory patients, the use of non-steroidal anti-inflammatory drugs (NSAIDs) and corticosteroids exacerbate the disease symptoms of COVID-19 patients, as they are often regarded as immunosuppressive drugs. Inhaled corticosteroids (ICS) are considered as first line treatment of asthma and chronic obstructive pulmonary disease (COPD). COVID-19 disease led the upper respiratory tract illness. ICS are used in the treatment of early symptoms of COVID-19 disease in low doses. Asthmatic patients or patients with chronic obstructive lung disease, who are on regular use of ICS were found to have a low risk of early symptoms of severely ill COVID-19 disease. Although there appeared to be some evidence that corticosteroid therapy may be beneficial in treatment of corona virus disease, but it is also reported to be applicable only at the early acute phase. The literature records revealed that injectable formulations of corticosteroids are known to suppress the immunity in patients infected with SARS-CoV2. The present review is to study the different formulations of corticosteroids and their possible use in COVID-19 progression. Quratulain Pirzada Somia Gul Faizan Baig ##submission.copyrightStatement## 2021-01-01 2021-01-01 6 01 1 7 10.21477/ijapsr.6.1.1