Antioxidant Activity of Dalbergia Melanoxylon Bark Extract

Swetha U

Abstract


The bark extract of Dalbergia melanoxylon (Fabaceae) was assessed for its antioxidant activity by in-vitro methods. This activity was evaluated by using various methods like hydrogen peroxide scavenging activity, Nitric oxide scavenging activity, DPPH radical scavenging activity and reducing power assay. Quantitative analysis of antioxidative components like total phenolic content, total flavonoid content and antioxidant capacity were estimated using spectrophotometric methods. The obtained results from this method are compared with ascorbic acid acts as a standard antioxidant drug. From the results it can concluded that the plant extract contains flavonoids and related polyphenols. And the extract has shown good scavenging activity in in-vitro methods. So the plant extract may be responsible for antioxidant activity.


Keywords


Dalbergia melanoxylon; antioxidant; total phenolic content; free radical scavenging; lipid peroxidation; methanolic extract;

Full Text:

PDF

References


Ahluwalia VK, Seshadri TR (1963). Dalberginone from heartwood of Dalbergia sissoo. Current Sci . 32(10):455.

Akinpelu DA, Aiyegoro OA, Okoh AI (2010). The in vitro antioxidant property of methanolic extract of Afzelia africana (Smith). Journal of Medicinal Plants Research, 4(19):2021-2027.

Aqil F, Ahmed I, Mehmood Z (2006). Antioxidant and free radical scavenging properties of twelve traditionally used Indian medicinal plants. Turkish Journal of Biology. 30:177-183.

Chacha M, Bjase-Moleta G, Majiinda RRT (2005). Antimicrobial and radical scavenging flavonoids from the stem wood of Erythrina latissima. Phytochemistry. 66:99-104.

Ghosh T, Maity TK, Bose A (2009). In vitro free radical scavenging activity of ethanolic extract of leaves of Cajanus cajana (L.) Millsp. Journal of Natural Remedies. 9(2):228-234.

Indu PK, Geeta T (2006). Screening methods for Antioxidants- A Review. Mini reviews in Medicinal Chemistry. 6:305-312.

Kuroda M, Uchida S, Watanabe K, Mimaki Y (2009). Chromones from the tubers of Eranthis cilicica and their antioxidant activity. Phytochemistry, 70:288-293.

Milan S Stankovic (2011). Total phenolic content, flavonoid concentration and antioxidant activity of Marrubium peregrinum extracts. kragujevac J.Sci. 33:63-72.

Nagulendran KR, Velavan S, Mahesh R, Hazeena BV (2007). In vitro Antioxidant activity and Total polyphenolic content of Cyperus rotundus Rhizomes. E-Journal of Chemistry, 4(3):440-449.

Prashant R Kaldhone (2009). Invitro antioxidant activity of methanolic extract of aerial parts of Canna indica L. Journal of pharmacy research, 2(11):1712-1715.

Ravi P, Narayanan V,Raman PV (1989). A novel quinone from Dalbergia sissoo. Indian Journal of Chemistry. 28B:778-779.

Sharma A, Chibber SS, Chawala HM (1980). Isocaviudin, A new isoflavone glucoside isolated from Dalbergia sissoo. Indian Journal of Chemistry. 237-238.

Susanta KM, Goutham C, Gupta M, Mazumdhar UK (2006). In vitro Antioxidant activity of Diospyros malabarica kostel bark. Indian Journal of Experimental Biology. 44:39-44.




DOI: http://dx.doi.org/10.21477/ijapsr.v2i04.9904

Refbacks

  • There are currently no refbacks.


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

Creative Commons License
International Journal of Applied Pharmaceutical Sciences and Research by Sierra Journals is licensed under a creativecommons.org/licenses/by/4.0/. https://creativecommons.org/licenses/by/4.0/
Based on a work at http://www.sierrajournals.com/direct/index.php/IJAPSR/issue/archive