Antibacterial activity of Euphorbia antiquorum latex

A.A.J.P Kumara, D.L Jayratne, G.V Samaranayake

Abstract


Euphorbia antiquorum is a large shrub or small tree belonging to the largest and the most diverse family in the plant kingdom, Euphorbiaceae. E. antiquram latex was used as a classical binding agent for the kshara sutra in the management of the anal fistula.
In the present study, an attempt was made to evaluate the antimicrobial properties of latex of E. antiquorum on certain microbes. The methanolic extract of the latex was prepared. The fractions of methanol extract were tested for their antibacterial activity against the Gram positive bacteria, Streptococus agalactiae and Staphylococcus aureus and Gram negative bacteria Escherichia coli and P. aeruginosa.
The results revealed that the latex showed minimum inhibition only to E. coli and S. aureus. Latex did not posses antibacterial activity against S. agalactiae and P. aeruginosa. The results suggest that the E. antiquorum latex extract account for the antibacterial properties and has a potential for use as an antimicrobial agent.

Keywords


Euphorbia antiquorum; antibacterial activity; anal fistula;

Full Text:

PDF

References


A.A.J.P. Kumara, D.L Jayaratne. Antibacterial activity of ksharasutra (medicated setone), in the management of the fistula in ano. Int. J. Res. Ayurveda Pharm. 7(4):36-41 http://dx.doi.org/10.7897/2277-4343.074129

Ananth BD, Reddy UMC (2010). Antimicrobial activity of methanol extract of Oxystelmaesculentum. J. pharm. Sci. Tech. 2:119-123.

Akinpelu DA, Onakoya TM (2006). Antimicrobial activities of medicinal plants used in folklore remedies in south – western. Afr. J. Biotech. 5:1078 - 1081.

Ferreira AM, Carvalho LH, Carvalho MJ, Sequeira MM, Silva AM, Jatrophane(2002) and Lathyrane diterpenoids from Euphorbia hyberna L. Phytochemistry; 61:373-377.

Jarvis I (2008). Immetient threat, Chem. Eng. News. 86: 21- 24

Kothia MB (1986) Bhagandara, A Study of Ksharasustra Therapy, Abstract paper in the 8th congress of research society for Ayurveda in Japan.

Khosravi A, Behzadi A (2006). Evaluation of the antibacterial activity of the seed hull of Quercusbarantii on some gram-negative bacteria, Pak. J. Med. Sci. 22:429-432.

Kupchan SM, Uchida I, Branfman AR, Dailey JRG, YuFei B (1976) Antileukemic principles isolated from Euphorbiaceae plants, Sci. 191: 571-572.

Mahesh B, Satish S (2008). Antimicrobial Activity of Some Important Medicinal Plant against Plant and Human Pathogens, World J. Agric. Sci. 4:839-843.

Martinez JL (2008). Antibiotics and antibiotic resistance gene in natural environments. Sci. 321:365 - 367.

Mitscher CA (2008). Coevolution: Mankind and Microbes. J. Nat. Prod. 71:497-509.

Sharath K, Krishna Mohan G, Sandhya Rani M, Kowmudi V, Suresh N (2016). Evaluation of Antibacterial and Antifungal Activity of Hexane and Methanol Extracts of Psoralea Corylifolea Seed. Int J App Pharm Sci Res. 1(1):25-30.

Siddique NA, Meyerb M, Najni AK, Akram M (2010). Evaluation of antioxidants activity, quantitative estimation of phenols and flavonoids in different parts of Aeglearmelo. Afr. J. Plant Sci. 4: 1-5.

Seyyednejad SM, Motamedi H (2010). A review on native medicinal plants in Khuzestan, Iran with antibacterial properties, Int. J. Pharmocol. 6: 551-560.

Sumathi S, Malathy N, Dharani B, Sinaprabha J, et al (2011) Antibacterial and antifungul activity of latex of Euphorbia antiquorum African Journal of Microbiology Research. 5(27):4753-4756.

Talib WH, Mahesneh AM (2010). Antimicrobial cytotoxicity and phytochemical screening of Jordian plants used in traditional medicine, Molecules. 15:1811-1824.

Unlu M, Unlu GV, Vural N, Donmez E, Cakmak O (2008). Composition and antimicrobial activity of Juniperusexcelsa essential oil. Chem. Nat. Com., 44:129-131.


Refbacks

  • There are currently no refbacks.


Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

Creative Commons License
International Journal of Applied Pharmaceutical Sciences and Research by Sierra Journals is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
Based on a work at http://www.sierrajournals.com/direct/index.php/IJAPSR/issue/archive.